名稱(chēng) | AI-Edigene® IDH2 p.R172K Reference Standard P |
型號(hào) | CBP10514 |
報(bào)價(jià) | ![]() |
特點(diǎn) | AI-Edigene® IDH2 p.R172K Reference Standard Plus |
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電話(huà):4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10514AI-Edigene® IDH2 p.R172K Reference Standard P

- 詳細(xì)內(nèi)容
CBP10514 | |
Format | Genomic DNA |
Description | IDH2 R172K lies within the active site of the Idh2 protein (PMID: 19228619). R172K confers a gain of function to Idh2, as indicated by the increased conversion of alpha-ketoglutarate to the onco-metabolite 2HG (R(-)-2-hydroxyglutarate) in cell culture (PMID: 20171147, PMID: 21326614). |
Technical Data | |
DNA Change | c.515G>A |
AA Change | p.R172K |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | NM_002168.4 |
Cosmic ID | COSM33733 |
Chr position(GRCh37) | chr15:90631838 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4°C |
Expiry | 36 months from the date of manufacture |