| 名稱(chēng) | AI-Edigene® IDH2 p.R140Q Reference Standard P |
| 型號(hào) | CBP10513 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | AI-Edigene® IDH2 p.R140Q Reference Standard Plus |
產(chǎn)品搜索
產(chǎn)品分類(lèi)
相關(guān)文章
- 免疫治療的下一個(gè)靶標(biāo)：腫瘤相關(guān)巨噬細(xì)胞？
- NK2R細(xì)胞篩選模型
- CD47/PD-(L)1 雙靶點(diǎn)細(xì)胞篩選模型簡(jiǎn)介
- 中國(guó)細(xì)胞資源庫(kù)，南京科佰生物
- 腫瘤免疫新型靶點(diǎn)——趨化因子受體
- 泛腫瘤大panel質(zhì)控品升級(jí)，免費(fèi)試用申請(qǐng)中
- 【產(chǎn)品推介】GLP1藥靶模型
- 【新品發(fā)布】DdPCR試劑盒開(kāi)發(fā)與驗(yàn)證
- ATCC細(xì)胞的細(xì)胞破碎
- TIGIT&PVRIG雙靶點(diǎn)細(xì)胞篩選模型
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10513AI-Edigene® IDH2 p.R140Q Reference Standard P
- 詳細(xì)內(nèi)容
CBP10513 | |
| Format | Genomic DNA |
| Description | IDH2 R140Q lies within the substrate binding region of the Idh2 protein (UniProt.org). R140Q confers a gain of function to Idh2, enabling conversion of alpha-ketoglutarate to the onco-metabolite 2HG (R(-)-2-hydroxyglutarate), results in increased 2HG levels in patient samples, and is transforming in cell culture (PMID: 20171147, PMID: 23558173). |
| Technical Data | |
| DNA Change | c.419G>A |
| AA Change | p.R140Q |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | NM_002168.4 |
| Cosmic ID | COSM41590 |
| Chr position(GRCh37) | chr15:90631934 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4°C |
| Expiry | 36 months from the date of manufacture |
" _ue_custom_node_="true">
會(huì)員_a.png)