| 名稱 | Claudin18.2/PANC-1 |
| 型號(hào) | CBP74143 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | Claudin18.2/PANC-1 |
產(chǎn)品搜索
相關(guān)文章
- 喝熱茶或使食管癌風(fēng)險(xiǎn)增加5倍
- 證據(jù)：鍛煉或許并不是控制體重的關(guān)鍵
- 關(guān)于sigma試劑的使用時(shí)長(zhǎng)相關(guān)說明
- 肺癌靶向治療：腫瘤不進(jìn)展時(shí)間超2年
- 一箭雙雕——IL-4R靶點(diǎn)和IL-4/IL-13雙重阻斷藥篩細(xì)胞模型
- IL36靶點(diǎn)藥物細(xì)胞篩選模型藥
- 腫瘤細(xì)胞培養(yǎng)實(shí)驗(yàn)的主要用途
- CCR8 | 潛在重磅腫瘤免疫治療靶點(diǎn)
- TIGIT&PVRIG雙靶點(diǎn)細(xì)胞篩選模型
- 重磅！科學(xué)家成功利用免疫細(xì)胞運(yùn)輸抗癌藥物至腫瘤靶點(diǎn)
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > 腫瘤免疫細(xì)胞株 > CBP74143Claudin18.2/PANC-1
- 詳細(xì)內(nèi)容
| CBP74143 | |
| I. Background | |
Claudins (CLDNs) are a family of proteins that form tight junctions and maintain the polarity of epithelial and endothelial cells. CLDN18 is specifically expressed in the stomach and lung. Of the two CLDN18 isoform transcripts produced by alternative splicing, CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific. CLDN18.2 is a highly selective gastric lineage antigen expressed exclusively on short-lived differentiated gastric epithelial cells where it has only limited accessibility to antibody drugs.14,15 CLDN18.2 is maintained during the course of malignant transformation and thus frequently displayed on the surface of human gastric cancer cells. | |
II. Introduction | |
| Host Cell: | PANC-1 |
| Expressed gene: | Claudin18.2 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+2ug/ml puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| III. Description of Host Cell Line | |
| Species: | Human |
| Disease: | A human pancreatic Beta cell: PANC-1 hybrid cell line. Insulin-secreting cell line. |
| Morphology: | Epithelial |
| Growth Properties: | Adherent |
| IV. Representative Data | |
1. Claudin18.2/PANC-1
| |
會(huì)員_a.png)