名稱 | PIK3CA p.H1047L Reference Standard 標(biāo)準(zhǔn)品 |
型號(hào) | CBP10320 |
報(bào)價(jià) | ![]() |
特點(diǎn) | PIK3CA p.H1047L Reference Standard |
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號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10320PIK3CA p.H1047L Reference Standard 標(biāo)準(zhǔn)品

- 詳細(xì)內(nèi)容
CBP10320 | |
Format | Genomic DNA |
Description | PIK3CA H1047L is a hotspot mutation that lies within the PI3K/PI4K domain of the Pik3ca protein (UniProt.org). H1047L confers a gain of function on the Pik3ca protein as indicated by increased phosphorylation of Akt and Mek1/2, growth factor-independent cell survival, and transformation in cell culture (PMID: 26627007, PMID: 29533785). |
Technical Data | |
DNA Change | c.3140A>T |
AA Change | p.H1047L |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50% |
Transcript | NM_006218.1 |
Cosmic ID | COSM776 |
Chr position(GRCh37) | chr3:178952085 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |