偷窥 性别 瘾 xxxxx,声声奶酥1v办公室,性色av蜜桃av人妻无码,欧洲精品99毛片免费高清观看

加入收藏 | 設(shè)為首頁 | 聯(lián)系我們

產(chǎn)品搜索

產(chǎn)品分類

聯(lián)系我們

聯(lián)系人:蔣經(jīng)理
電話:4008750250
號碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com

產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > 腫瘤免疫細(xì)胞株 > CBP74010CSF1R/SRE-Luc/HEK293

CSF1R/SRE-Luc/HEK293
名稱 CSF1R/SRE-Luc/HEK293
型號 CBP74010
報價
特點(diǎn) CSF1R/SRE-Luc/HEK293,凍存條件:90% FBS+10% DMSO
  • 詳細(xì)內(nèi)容
CBP74010
I. Background

Colony Stimulating Factor 1 Receptor (CSF1R, CD115, M-CSF-R) is the receptor for the cytokine CSF1 (MCSF; CSF-1), which controls the growth, function, and differentiation of macrophages. This interaction drives the development and survival of Tumor-Associated Macrophages (TAMs), which in turn suppress the local immune response to the cancer. An alternative ligand is IL-34, which has been implicated in neuroprotective and survival signals following brain injury and neurodegeneration.

As a tyrosine kinase transmembrane receptor, activation of CSF1R by its ligand initiates a vast array of intracellular activity, including activation of the MAPK/ERK signaling pathway. When phosphorylated by ERK, Elk1 forms a complex with Serum Response Factor (SRF) and binds to Serum Response Element (SRE), resulting in the expression of numerous mitogen-inducible genes.

Ⅱ. Introduction
Host Cell:HEK293
Expressed gene:

CFS1R-SRE-Luciferase

Stability:32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s):FMS, CD115
Freeze Medium:90% FBS+10% DMSO
Culture Medium:

DMEM +10%FBS+200ug/ml hygromycin+1ug/ml puromycin

Mycoplasma Testing:Negative
Storage:Liquid nitrogen
Application(s):Functional(Report Gene) Assay
Ⅲ. Description of Host Cell Line
Organism:Human
Tissue:Embryonic kidney
Morphology: Epitheloid cell
Growth Properties: Adherent
Ⅳ. Representative Data

CBP74010-1.png

Figure 1. Recombinant HEK293 cell line expressing firefly luciferase gene under the control of SRE response elements with constitutive expression of CSF1R(Colony Stimulating Factor 1 Receptor)

CBP74010-2.png

Figure 2. Detect Luciferase assay by Ultra Luciferase Detection Kit CBPH0001(we strongly suggest to purchase from Cobioer).HEK293/CFS1R-SRE Luciferase Reporter cells were stimulated by CSF1, the EC50 was 3.75ng/ml.

CBP74010-3.png

Figure 3. Inhibition of CSF1 (100 ng/ml) -induced SRE reporter actity by CSF1R inhibitors.






如果你對CBP74010CSF1R/SRE-Luc/HEK293感興趣,想了解更詳細(xì)的產(chǎn)品信息,填寫下表直接與廠家聯(lián)系:


留言框

  • 產(chǎn)品:

  • 您的單位:

  • 您的姓名:

  • 聯(lián)系電話:

  • 常用郵箱:

  • 省份:

  • 詳細(xì)地址:

  • 補(bǔ)充說明:

  • 驗(yàn)證碼:

    請輸入計算結(jié)果(填寫阿拉伯?dāng)?shù)字),如:三加四=7

化工儀器網(wǎng)

推薦收藏該企業(yè)網(wǎng)站
无遮挡h纯肉动漫在线播放| 偷偷鲁2020精品偷拍视频| 久久黄色网站| 国产69tv精品久久久久99| 亚洲视频一区| 人妻精油按摩bd高清中文字幕| 熟妇高潮喷沈阳45熟妇高潮喷| 一本久道久久综合狠狠爱| 日本理伦片午夜理伦片| 日本韩国男男作爱gaywww| 精东影视传媒MV国产剧能看不 | 久久人人爽人人爽人人片av不| 成全动漫视频在线观看| av无码专区| 警察受被粗汉h玩松了尿进去双性| 久久精品熟女亚洲av麻豆| 偷朋友人妻系列h文| 在线天堂中文最新版网| 国产精品99亚发布| 国产精品毛片大码女人| 扒开双腿疯狂进出爽爽爽动态照片| 中文字幕乱码中文乱码| 日本理伦片午夜理伦片| 人妻久久久一区二区三区| 国产成人一区二区三区传媒| 诱人的女同学hd中文字幕| 邻居老头把我弄舒服死了| 久久久国产精华液| 嗯啊小sao货奶头好硬视频| 国产精品18久久久久久不卡| 男男体育生控精自慰打飞| 国产精品久久久| 善良的嫂子在线观看| 被窝里的翁憩二十六| 国产精品打着电话偷着情| 日本16岁rapper| 男人放进女人阳道视频观看| 曰批视频免费40分钟试看| 撕开胸罩一边亲一边摸| 国产69精品久久久久人妻刘玥| 特级做a爰片毛片免费69|